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TLR7 Rabbit Polyclonal Antibody

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SKU
TA336419
Rabbit Polyclonal TLR7 Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $620.00
5 Days*
Bulk/Customize

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Specifications
Specifications
Product Data
Application FC, IHC
Recommended Dilution Flow Cytometry, Flow (Intracellular): 0.5 - 2 ug/1x10^6 cells, Immunohistochemistry: 1:10 - 1:500, Immunohistochemistry-Paraffin: 1:10 - 1:50, Flow (Cell Surface), Immunohistochemistry-Frozen: 1:20
Reactivity Human, Mouse
Antibody Host Rabbit
Clonality Polyclonal
Immunogen This antibody was developed against KLH-conjugated synthetic peptide corresponding to a portion of amino acids 684-701 of human TLR7 (NP_057646).
Buffer PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name toll like receptor 7
Database Link
Background The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1-10) have been described. Stimulation of the NFkB signaling pathway by TLR7 suggests that it plays a role in immune response.
Synonyms TLR7-like
Note Flow Cytometry: (Cell Surface): see Wong et al, 2007 for details Immunohistochemistry-Frozen: (1:20) (see product citation, Chen et al., 2005)
Reference Data
Protein Categories ADC Targets, Allergies and autoimmune diseases, Chemokines, Cytokines, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Toll-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.