VDAC2 Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | Western Blot: 1-3 ug/ml |
Reactivity | Bovine, Canine, Feline, Human, Primate |
Antibody Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Amino acids 120-132 (KKSGKIKSSYKRE) of human VDAC2 protein were used as the immunogen. |
Buffer | PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Protein G purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | voltage dependent anion channel 2 |
Database Link | |
Background | Voltage-dependent anion channels (VDAC) are small pore-forming membrane proteins that regulate metabolite exchange across the mitochondrial outer membrane. Apart from metabolite transfer, VDAC role has also been suggested during apoptosis. VDAC2 is one of the isoforms of VDAC. It interacts with BAK and functions as a specific inhibitor of BAK-dependent mitochondrial apoptosis. |
Synonyms | POR |
Reference Data | |
Protein Families | Druggable Genome, Ion Channels: Other |
Protein Pathways | Calcium signaling pathway, Huntington's disease, Parkinson's disease |
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