KAT7 Rabbit Polyclonal Antibody

CAT#: TA332940

Rabbit anti-KAT7 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using KAT7 antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human KAT7
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 611
• Gene Name: lysine acetyltransferase 7
• Database Link:
  NP_008998
  Entrez Gene 217127 MouseEntrez Gene 303470 RatEntrez Gene 11143 Human
  UniProt ID O95251
• Background: MYST2, also named as HBO1, HBOa MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, belongs to the MYST (SAS/MOZ) family. It specifically represses AR mediated transcription. MYST2 is a candidate oncogene. It enhances the anchorage-independent growth of breast cancer cells.(PMID:19372580) MYST2 is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. It is an important downstream molecule of ERa, and ERK1/2 signaling pathway may involved in the expression of HBO1 increased by E2.
• Synonyms: HBO1; HBOA; MYST2; ZC2HC7

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors