RNF2 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ChIP, ELISA, ICC, IHC, IP, WB |
|---|---|
| Recommended Dilution | WB:1/500-1000 IHC:1/50-200 ICC/IF:1/50-200 IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells. ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Buffer | Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 38kDa |
| Gene Name | ring finger protein 2 |
| Database Link | |
| Background | Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. |
| Synonyms | BAP-1; BAP1; DING; HIPI3; RING1B; RING2 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
The oncogenic impact of RNF2 on cell proliferation, invasion and migration through EMT on mammary carcinoma
Wu, Wang, Li et al
Pathol Res Pract (2019) 215 (9), 152523 DOI: 10.1016/j.prp.2019.152523
Wu, Wang, Li et al
Pathol Res Pract (2019) 215 (9), 152523 DOI: 10.1016/j.prp.2019.152523
Cited by 14
AI Summary: OriGene products, specifically the RNF2 overexpression plasmid (RC209307) and RNF2 shRNA plasmid (TL313307), were used in this study to manipulate RNF2 expression levels in mammary carcinoma cell lines, enabling the investigation of RNF2's role in promoting cell proliferation, migration, and invasion.
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
