MCM5 Rabbit Polyclonal Antibody

CAT#: TA332761

Rabbit anti-MCM5 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using MCM5 antibody.

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  Immunofluorescence analysis of U20S cell using MCM5 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, IP, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50 - 1:200;IP 1:20 - 1:50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human MCM5
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 82 kDa
• Gene Name: minichromosome maintenance complex component 5
• Database Link:
  NP_006730
  Entrez Gene 17218 MouseEntrez Gene 291885 RatEntrez Gene 4174 Human
  UniProt ID P33992
• Background: The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
• Synonyms: CDC46; P1-CDC46

Reference Data

• Protein Families: Stem cell - Pluripotency, Transcription Factors
• Protein Pathways: Cell cycle, DNA replication