GCLM Rabbit Polyclonal Antibody
Rabbit anti-GCLM Polyclonal Antibody
Product Datasheet for 'TA332604'
|Applications||IF, IHC, WB|
|Recommend Dilution||WB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Recombinant protein of human GCLM|
|Formulation||Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Predicted Protein Size||274|
|Gene Name||glutamate-cysteine ligase modifier subunit|
|Background||Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.|
|Protein Families||Druggable Genome|
|Protein Pathways||Glutathione metabolism, Metabolic pathways|
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