MVP Rabbit Polyclonal Antibody
Rabbit anti-MVP Polyclonal Antibody
Product Datasheet for 'TA332484'
|Recommend Dilution||WB 1:500 - 1:2000, IHC 1:50- 1:200|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Recombinant protein of human MVP|
|Formulation||Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Predicted Protein Size||893|
|Gene Name||major vault protein|
|Background||This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.|
|Protein Families||Druggable Genome|
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