H2BC21 Rabbit Polyclonal Antibody

CAT#: TA332475

Rabbit anti-HIST2H2BE Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using HIST2H2BE antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat, Other (Wide Range)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human HIST2H2BE
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 126
• Gene Name: histone cluster 2, H2be
• Database Link:
  NP_003519
  Entrez Gene 319190 MouseEntrez Gene 295274 RatEntrez Gene 8349 Human
  UniProt ID Q16778
• Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
• Synonyms: GL105; H2B; H2B.1; H2BFQ; H2BGL105; H2BQ

Reference Data

• Protein Pathways: Systemic lupus erythematosus