POLR2C Rabbit Polyclonal Antibody

CAT#: TA332432

Rabbit anti-POLR2C Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using POLR2C antibody.

Specifications

Product Data

• Applications: IP, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant Protein of human POLR2C
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 275
• Gene Name: polymerase (RNA) II subunit C
• Database Link:
  NP_116558
  Entrez Gene 20021 MouseEntrez Gene 5432 Human
  UniProt ID P19387
• Background: This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.
• Synonyms: hRPB33; hsRPB3; RPB3; RPB31

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase