SRCAP Goat Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 5-10ug/ml |
| Reactivity | Dog, Human (Expected from sequence similarity: Mouse, Pig), Rat |
| Antibody Host | Goat |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Peptide with sequence C-QEGNDAEAQRREIE, from the internal region (near N Trminus) of the protein sequence according to NP_006653.2 |
| Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Concentration | lot specific |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | Snf2-related CREBBP activator protein |
| Database Link | |
| Background | This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. provided by RefSeq, Feb 2012 |
| Synonyms | DOMO1; EAF1; FLHS; SWR1 |
| Note | IHC: In paraffin embedded Human Skin shows nuclear staining in some keratinocytes. |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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