HTR2B Rabbit Polyclonal Antibody

SKU
TA329175
Rabbit Polyclonal anti-HTR2B antibody
  $585.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application IF, WB
Recommended Dilution WB, IF
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-HTR2B antibody: synthetic peptide directed towards the N terminal of human HTR2B. Synthetic peptide located within the following region: QTESIPEEMKQIVEEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKK
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 54 kDa
Gene Name 5-hydroxytryptamine receptor 2B
Database Link
Background Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
Synonyms 5-HT(2B); 5-HT2B
Note Immunogen sequence homology: Human: 100%; Bovine: 100%; Horse: 93%; Pig: 87%; Guinea pig: 85%; Dog: 80%
Reference Data
Protein Categories Cytokines, GPCR, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Calcium signaling pathway, Gap junction, Neuroactive ligand-receptor interaction
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