CLK4 Rabbit Polyclonal Antibody

CAT#: TA329164

Rabbit Polyclonal anti-CLK4 antibody

Product Images

WB Suggested Anti-CLK4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain

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  Sample type: human microvascular endothelial cells (25ug); Primary Dilution: 1:1000; Secondary Antibody: Goat anti-Rabbit-HRP; Secondary Dilution: 1:5000; Image Submitted by: Andreas Eisenreich ; Charite Universitatsmedizin Berlin

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-CLK4 antibody: synthetic peptide directed towards the N terminal of human CLK4. Synthetic peptide located within the following region: RSRRSSPKRKRNRHCSSHQSRSKSHRRKRSRSIEDDEEGHLICQSGDVLR
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 57 kDa
• Gene Name: CDC like kinase 4
• Database Link:
  NP_065717
  Entrez Gene 57396 Human
  UniProt ID Q9HAZ1
• Background: The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
• Synonyms: DKFZp686A20267
• Note: Immunogen sequence homology: Dog: 100%; Pig: 100%; Human: 100%; Rabbit: 100%; Guinea pig: 100%; Rat: 93%; Horse: 93%; Bovine: 93%; Yeast: 91%; Mouse: 86%

Reference Data

• Protein Families: Druggable Genome, Protein Kinase