Ghsr Rabbit Polyclonal Antibody
$1,145.00
3 Weeks*
Specifications
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | WB: 1:200-1:2000; FC: 1:50-1:600 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Peptide CRATEFAVRSG, corresponding to amino acid residues 197-207 of rat Ghrelin Receptor. 2nd extracellular loop. |
| Buffer | Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3. |
| Reconstitution Method | Add 50 ul double distilled water (DDW) to the lyophilized powder. |
| Purification | Affinity purified on immobilized antigen. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Gene Name | growth hormone secretagogue receptor |
| Database Link | |
| Background | Ghrelin is a 28 amino acid peptide, acylated on a serine residue which is essential for its biological activity. In rodents, an additional form of the peptide could be purified. The peptide is released from the stomach and exerts its effect to ghrelin receptor (GHS-R). GHS-R is a member of the G-protein coupled receptor (GPCR) superfamily. Like all members, the receptor has seven transmembrane spanning domains and upon activation it stimulates phospholipase C, thereby increasing IP3 and intracellular Ca2+ levels. GHS-R is expressed in the hypothalamus, pituitary and hippocampus. Some of the actions of ghrelin include the stimulation of growth hormone release, food intake, fat accumulation, regulation of memory and learning, activation of reward-related pathways and neuroprotection to name a few. GHS-R 1b is a truncated form of the full length receptor which is also expressed. Although its exact functions are unknown, it is believed that it may be involved in downregulating signaling from the full length receptor. In addition, it is overexpressed in lung cancer where it dimerizes with neurotensin receptor. |
| Synonyms | GHRP; GHS-R; OTTHUMP00000211093 |
| Note | This antibody was tested in live cell imaging. Please see IF/ICC data for detail. |
| Reference Data | |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
