Trpv4 Rabbit Polyclonal Antibody
Rabbit Polyclonal Anti-TRPV4
Product Datasheet for 'TA328742'
|Applications||IF, IHC, WB|
|Recommend Dilution||WB: 1:200-1:2000; IHC: 1:100-1:3,000; FC: 1:50-1:600|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Peptide CDGHQQGYAPKWRAEDAPL, corresponding to amino acid residues 853-871 of rat TRPV4.Â Intracellular, C-terminus.|
|Formulation||Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.|
|Purification||Affinity purified on immobilized antigen.|
|Gene Name||transient receptor potential cation channel, subfamily V, member 4|
|Background||TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1 According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology; TRPC, TRPM and TRPV (to date, three extra subfamilies are considered to belong to the TRP family; the TRPA, TRPML, and TRPP). The TRPV subfamily consists of six members, TRPV1-6. TRPV4 (also named OTRPC4) is activated under hypotonic conditions and serves as an osmoreceptor. TRPV4 is expressed in brain, liver, kidney, heart, testis and salivary gland.|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.