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Adrb3 Rabbit Polyclonal Antibody

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SKU
TA328711
Rabbit Polyclonal Anti-beta3-Adrenoceptor (extracellular)
Size:
50 ul
Conjugation:
Unconjugated
  $1,145.00
3 Weeks*
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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 1:200-1:2000; IHC: 1:100-1:3000
Reactivity Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Peptide DAEAQESH*SNPRC, corresponding to amino acid residues 180-192 of mouse Ã?3-Adrenoceptor with replacement of cysteine 186 (C186) with serine (*S). 2nd extracellular loop.
Buffer Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Reconstitution Method Add 50 ul double distilled water (DDW) to the lyophilized powder.
Purification Affinity purified on immobilized antigen.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Gene Name adrenergic receptor, beta 3
Database Link
Background Adrenoceptors (also called Adrenergic receptors) are the receptors for the catecholamines adrenaline and noradrenaline (called epinephrine and norepinephrine in the United States). Adrenaline and noradrenaline play important roles in the control of blood pressure, myocardial contractile rate and force, airway reactivity, and a variety of metabolic and central nervous system functions. The Adrenoceptors are members of the G-protein-coupled receptor (GPCR) superfamily of membrane proteins. They share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus.The Adrenoceptors are divided into three types: a1, a2 and Ã?-Adrenoceptors. Each type is further divided into at least three subtypes: a1A, a1B, a1D, a2A, a2B, a2C, Ã?1, Ã?2, Ã?3. The Adrenoceptors are expressed in nearly all peripheral tissues and in the central nervous system. The Ã?3-Adrenoceptor is insensitive to the commonly used Ã?-antagonists and has often been referred to as the 'atypical' Ã?-Adrenoceptor. Mouse Ã?3-Adrenoceptor has two known splice variants, isoforms Ã?3a-Adrenoceptor and Ã?3b-Adrenoceptor. Both isoforms are expressed in white and brown adipose tissues. The Ã?3b-Adrenoceptor is highly exspressed in brain. The Ã?3- Adrenoceptor has been found to play a key role in the lipolytic action of catecholamines.
Synonyms ADRB3R; B3AR; BETA3AR; FLJ99960
Reference Data
Protein Categories Endocrine and metabolic diseases, GPCR, Membrane Proteins
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Documents
Resources

file-alt Citations

Amniotic fluid stem cell-derived extracellular vesicles enhance functional recovery of neurogenic bladder and neurovascular plasticity after cerebral ischemia in rats
Liang, Shaw, Wu et al
Life Sci (2026) 389, 124225 DOI: 10.1016/j.lfs.2026.124225
Cited by 1
AI Summary: In this study, OriGene's β3-adrenoceptor antibody (Cat. No. TA328711) was used to assess bladder protein expression, contributing to the evaluation of molecular changes underlying the therapeutic effects of amniotic fluid stem cell-derived extracellular vesicles on neurogenic bladder recovery after cerebral ischemia in rats.
Snippet: …ab108319, 0.281 mg/mL, 1:500, Abcam, Cambridge, UK), β3-adrenoceptor (rabbit polyclonal IgG, Cat. No. TA328711, 0.5 g/mL, 1:200, OriGene, MD, USA),
Showing 1-1 of 1 papers.
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