BLMH Rabbit Polyclonal Antibody

CAT#: TA328161

Rabbit polyclonal anti-BLMH antibody (Center)

Product Images

BLMH Antibody (Center) (Cat. #TA328161) western blot analysis in K562 cell line, mouse stomach and rat stomach tissue lysates (35ug/lane).This demonstrates the BLMH antibody detected the BLMH protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse, Rat (Predicted: Rabbit)
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This BLMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the Central region of human BLMH.
• Formulation: PBS with 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: bleomycin hydrolase
• Database Link:
  NP_000377
  Entrez Gene 104184 MouseEntrez Gene 287552 RatEntrez Gene 642 Human
  UniProt ID Q13867
• Background: The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).
• Synonyms: BH; BMH

Reference Data

• Protein Families: Druggable Genome, Protease