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STAT2 Rabbit Polyclonal Antibody [Clone ID: Poly6245]
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USD 436.00
USD 200.00
USD 867.00
Specifications
| Product Data | |
| Clone Name | Poly6245 |
| Applications | WB |
| Recommended Dilution | WB, IP |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Peptide mapping to the carboxy terminus of human STAT2 |
| Formulation | This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% gelatin. |
| Purification | The antibody was purified by antigen-affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 113 kD |
| Gene Name | signal transducer and activator of transcription 2 |
| Database Link | |
| Background | STAT2, a 113 kD member of the STAT (signal transducer and activators of transcription) protein family, is phosphorylated in response to interferon alpha receptor signaling by Janus kinase I. Phosphorylation of STAT 2 induces nuclear translocation to activate transcription. STAT2 is highly expressed in the skin and thymus. STAT 2 forms complex with STAT1 and p48 to activate transcription and does not bind DNA directly. STAT 3 interacts with interferon regulatory factor 9, interferon alpha receptor, STAT 1, p48, and CREB binding protein. The Poly6245 antibody recognizes the C-terminal region of human STAT2 and has been shown to be useful for Western blotting, immunoprecipitation, and immunohistochemistry. |
| Synonyms | IMD44; ISGF-3; P113; STAT113 |
| Reference Data | |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Chemokine signaling pathway, Jak-STAT signaling pathway |
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