ADA Rabbit Polyclonal Antibody

CAT#: TA326892

ADA Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using ADA antibody.

• 

  Immunofluorescence analysis of U2OS cell using ADA antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50- 1:200
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ADA
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adenosine deaminase
• Database Link:
  NP_000013
  Entrez Gene 24165 RatEntrez Gene 100 Human
  UniProt ID P00813
• Background: This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. [provided by RefSeq, Jul 2008]
• Synonyms: adenosine aminohydrolase; adenosine deaminase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Primary immunodeficiency, Purine metabolism