IL36RN Rabbit Polyclonal Antibody

SKU
TA326668
Rabbit Polyclonal IL-36RN Antibody
  $640.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen IL-36RN antibody was raised against a 19 amino acid peptide near the carboxy terminus of human IL-36RN.
Buffer IL-36RN antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification IL-36RN antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size Predicted: 17 kDa; Observed: 27 kDa
Gene Name interleukin 36 receptor antagonist
Database Link
Background IL-36RN is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36RN specifically inhibits the activation of NF-kappaB induced IL-36A (2). The opposing activities of these cytokines have been suggested to be involved in the regulation of skin inflammation (3). Like the IL-36 cytokines (IL-36A, IL-36B and IL-36G), IL-36RN requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (4).
Synonyms FIL1; FIL1(DELTA); FIL1D; IL-36Ra; IL1F5; IL1HY1; IL1L1; IL1RP3; IL36RA; PSORP; PSORS14
Reference Data
Protein Categories Cytokines, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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