PHF14 Rabbit Polyclonal Antibody

CAT#: TA326658

Rabbit Polyclonal PHF14 Antibody

Product Images

Western blot analysis of PHF14 in 293 cell lysate with PHF14 antibody at 1 ug/ml.

• 

  Immunofluorescence of PHF14 in 293 cells with PHF14 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PHF14 antibody was raised against a 19 amino acid peptide near the amino terminus of human PHF14.
• Formulation: PHF14 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: PHF14 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 98 kDa; Observed: 100 kDa
• Gene Name: PHD finger protein 14
• Database Link:
  NP_055475
  Entrez Gene 75725 MouseEntrez Gene 500030 RatEntrez Gene 9678 Human
  UniProt ID O94880
• Background: PHF14, a novel plant homology domain (PHD) transcription factor, controls the proliferation of mesenchymal cells by regulating PDGFR alpha expression in embryonic development (1). PHD finger transcription factors are concerned with transcriptional regulation by interacting with modified histones (2), and dysregulation of several genes encoding PHD finger transcription factors, such as ING1 and RBP2, has been found in human cancer diseases suggesting these factors have an important role for cancer cell proliferation. PHF14 is a potential target for new treatments of lung fibrosis (1, 3).
• Synonyms: MGC176640

Reference Data

• Protein Families: Druggable Genome, Transcription Factors