MMP9 Rabbit Polyclonal Antibody

CAT#: TA326652

Rabbit Polyclonal MMP9 Antibody

Product Images

Western blot analysis of MMP9 in mouse lung tissue lysate with MMP9 antibody at 1 ug/ml.

• 

  Immunohistochemistry of MMP9 in human lung tissue with MMP9 antibody at 2.5 ug/mL.

• 

  Immunofluorescence of MMP9 in human lung tissue with MMP9 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MMP9 antibody was raised against a 16 amino acid peptide near the center of human MMP9.
• Formulation: MMP9 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: MMP9 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 76 kDa; Observed: 73 kDa
• Gene Name: matrix metallopeptidase 9
• Database Link:
  NP_004985
  Entrez Gene 17395 MouseEntrez Gene 81687 RatEntrez Gene 4318 Human
  UniProt ID P14780
• Background: The matrix metalloproteinase (MMP) family are a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases (1). MMP9 degrades type IV and V collagens (2) and studies suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow (3) and plays a role in tumor-associated tissue remodeling (4).
• Synonyms: CLG4B; GELB; MANDP2; MMP-9

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Bladder cancer, Leukocyte transendothelial migration, Pathways in cancer