VNN3 Rabbit Polyclonal Antibody

CAT#: TA326633

Rabbit Polyclonal VNN3 Antibody

Product Images

Western blot analysis of VNN3 in human brain tissue lysate with VNN3 antibody at (A) 0.5 and (B) 1 ug/mL.

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  Immunohistochemistry of VNN3 in human liver tissue with VNN3 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 0.5 and 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: VNN3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human VNN3.
• Formulation: VNN3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: VNN3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: vanin 3
• Database Link:
  NP_060869
  Entrez Gene 26464 MouseEntrez Gene 498992 RatEntrez Gene 55350 Human
  UniProt ID Q9NY84
• Background: VNN3 Antibody: The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.
• Synonyms: HSA238982; MGC124285; MGC171203; OTTMUSP00000022908; PAGEL-beta; PAGEL-eta; PAGEL-zeta; vanin 3; vascular non-inflammatory molecule 3

Reference Data

• Protein Families: Transmembrane