Superoxide Dismutase 3 (SOD3) Mouse Monoclonal Antibody [Clone ID: 4GG11G6]
Specifications
| Product Data | |
| Clone Name | 4GG11G6 |
|---|---|
| Application | IF |
| Recommended Dilution | WB: 1:1000, IHC: 1:100, ICC: 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Immunogen | Human EC SOD purified from aortas |
| Buffer | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Concentration | lot specific |
| Purification | Protein G Purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | superoxide dismutase 3, extracellular |
| Database Link | |
| Background | Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body . It works by catalyzing the dismutation of the superoxide radical O2? to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase . In general, SODs play a major role in antioxidant defense mechanisms . There are three types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge . The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space . SOD3 can also be distinguished by its heparin-binding capacity . |
| Synonyms | EC-SOD |
| Note | Detects EC SOD at ~35kDa. |
| Reference Data | |
| Protein Categories | Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
Reviews
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| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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