NF2 Rabbit Polyclonal Antibody

CAT#: TA325711

Rabbit Polyclonal Merlin (Ser518) Antibody (Phospho-specific)

Product Images

Western blot analysis of Merlin phosphorylation expression in IFN-a treated HuvEc whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human Merlin around the phosphorylation site of Serine 518
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 70 kDa
• Gene Name: neurofibromin 2 (merlin)
• Database Link:
  NP_000259
  Entrez Gene 18016 MouseEntrez Gene 25744 RatEntrez Gene 4771 Human
  UniProt ID P35240
• Background: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport.
• Synonyms: ACN; BANF; SCH

Reference Data

• Protein Families: Druggable Genome