KLF4 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | WB:1/2000, IHC-P:1/50-200, IF:1/10-50 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-101 amino acids from the N-terminal region of human KLF4. |
| Specificity | This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-101 amino acids of human KLF4. |
| Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 54.7 kDa |
| Gene Name | Kruppel-like factor 4 (gut) |
| Database Link | |
| Background | Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development Contributes to the down-regulation of p53/TP53 transcription. |
| Synonyms | EZF; GKLF |
| Reference Data | |
| Protein Families | Adult stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Inhibitory effect of ginsenoside Rg3 on cancer stemness and mesenchymal transition in breast cancer via regulation of myeloid-derived suppressor cells
Song, Eum, Park et al
PLoS One (2020) 15 (10), e0240533 DOI: 10.1371/journal.pone.0240533
Song, Eum, Park et al
PLoS One (2020) 15 (10), e0240533 DOI: 10.1371/journal.pone.0240533
Cited by 40
AI Summary: In this study, the OriGene KLF4 antibody (cat. #TA324722) was used to assess the expression of KLF4, a key marker involved in cancer stemness, thereby contributing to the evaluation of ginsenoside Rg3's inhibitory effects on breast cancer progression.
Snippet: 610154, BD Biosciences), NOTCH1 (cat. #6014, Santa Cruz Biotechnology), OCT4 (cat. #611203, BD Biosciences), KLF4 (cat. #TA324722, OriGene, MD, USA), Vimentin (cat. #550513, BD Biosciences), NOTCH2 (cat. #5732, Cell Signaling Technology), and β-Actin Cached;- 610154, BD Biosciences), NOTCH1 (cat. #6014, Santa Cruz Biotechnology), OCT4 (cat. #611203, BD Biosciences), KLF4 (cat. #TA324722, OriGene, MD, USA), Vimentin (cat. #550513, BD Biosciences), NOTCH2 (cat. #5732, Cell Signaling Technology), and β-Actin Cached
Showing 1-1 of 1 papers.
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