MUC5B Rabbit Polyclonal Antibody

CAT#: TA324304

Anti-MUC5B Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA324304 (MUC5B Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA324304 (MUC5B Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: LOVO cell lysate
  IHC: 50-100
  Positive control: Human liver cancer
  Predicted cell location: Secreted
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 5750-5762 amino acids of human mucin 5B, oligomeric mucus/gel-forming
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mucin 5B, oligomeric mucus/gel-forming
• Database Link:
  NP_002449
  Entrez Gene 727897 Human
  UniProt ID Q9HC84
• Background: This gene encodes a member of the mucin family of proteins; which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva; normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases; including sinus mucosa of chronic rhinosinusitis (CRS); CRS with nasal polyposis; chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease; and it may be involved in the pathogenesis of these diseases.
• Synonyms: MG1; MUC-5B; MUC5; MUC9