SPDEF Rabbit Polyclonal Antibody

CAT#: TA324209

Anti-SPDEF Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA324209 (SPDEF Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA324209 (SPDEF Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-100
  Positive control: Human colorectal cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 129-332 amino acids of human SAM pointed domain containing ets transcription factor
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SAM pointed domain containing ETS transcription factor
• Database Link:
  NP_036523
  Entrez Gene 30051 MouseEntrez Gene 25803 Human
  UniProt ID O95238
• Background: The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells; and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain; breast; lung and ovarian tumors; compared to the corresponding normal tissues; and it shows better tumor-association than other cancer-associated molecules; making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: bA375E1.3; PDEF

Reference Data

• Protein Families: Transcription Factors