STEAP4 Rabbit Polyclonal Antibody

SKU
TA324151
Anti-STEAP4 Rabbit Polyclonal Antibody
  $305.00
In Stock*
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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 25-100
Positive control: Human cervical cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 441-456 amino acids of human STEAP family member 4
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name STEAP4 metalloreductase
Database Link
Background The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family; and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+); using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism; and may contribute to the normal biology of the prostate cell; as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms STAMP2; TIARP; TNFAIP9
Reference Data
Protein Categories Membrane Proteins
Protein Families Druggable Genome, Transmembrane
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