STEAP4 Rabbit Polyclonal Antibody

SKU TA324150

Anti-STEAP4 Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 200-1000; WB positive control: HepG2 cell lysate; IHC: 40-200; Positive control: Human liver cancer; Predicted cell location: Cell membrane
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 441-456 amino acids of human STEAP family member 4
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: STEAP4 metalloreductase
• Database Link:
  NP_078912
  Q687X5
• Background: The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family; and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+); using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism; and may contribute to the normal biology of the prostate cell; as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: STAMP2; TIARP; TNFAIP9

Reference Data

• Protein Families: Druggable Genome, Transmembrane