TRPV4 Rabbit Polyclonal Antibody
Anti-TRPV4 Rabbit Polyclonal Antibody
Product Datasheet for 'TA324061'
|Recommend Dilution||ELISA: 1:2000-10000, IHC: 1:50-200|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Fusion protein corresponding to a region derived from 237-465 amino acids of human transient receptor potential cation channel, subfamily V, member 4|
|Formulation||PBS pH7.3, 0.05% NaN3, 50% glycerol|
|Purification||Antigen affinity purification|
|Gene Name||transient receptor potential cation channel subfamily V member 4|
|Background||This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable; nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||BCYM3; CMT2C; HMSN2C; OTRPC4; SMAL; SPSMA; SSQTL1; TRP12; VRL2; VROAC|
|Protein Families||Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane|
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