IL1RAP Rabbit Polyclonal Antibody

CAT#: TA324046

Anti-IL1RAP Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-4: Hela cell Mouse heart tissue Human cerebella tissue Human cerebrum tissue lysates Primary antibody: TA324046 (IL1RAP Antibody) at dilution 1/600 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 30 seconds

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA324046 (IL1RAP Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA324046 (IL1RAP Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA324046 (IL1RAP Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA324046 (IL1RAP Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cell, Mouse heart tissue, Human cerebella tissue, Human cerebrum tissue lysates
  IHC: 50-200
  Positive control: Human gastric cancer
  Predicted cell location: Secreted
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 22-356 amino acids of Human Interleukin-1 receptor accessory protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 1 receptor accessory protein
• Database Link:
  NP_608273
  Entrez Gene 16180 MouseEntrez Gene 25466 RatEntrez Gene 3556 Human
  UniProt ID Q9NPH3
• Background: Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection; tissue damage; or stress; by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms; one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
• Synonyms: C3orf13; IL-1RAcP; IL1R3

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction