IL1RAP Rabbit Polyclonal Antibody

SKU TA324046

Anti-IL1RAP Rabbit Polyclonal Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Hela cell, Mouse heart tissue, Human cerebella tissue, Human cerebrum tissue lysates; IHC: 50-200; Positive control: Human gastric cancer; Predicted cell location: Secreted
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 22-356 amino acids of Human Interleukin-1 receptor accessory protein
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: interleukin 1 receptor accessory protein
• Database Link:
  NP_608273
  Q9NPH3
• Background: Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection; tissue damage; or stress; by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms; one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
• Synonyms: C3orf13; IL-1RAcP; IL1R3

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction