AMHR2 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 50-200 Positive control: Human cervical cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 203-518 amino acids of human anti-Mullerian hormone receptor, type II |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | anti-Mullerian hormone receptor type 2 |
| Database Link | |
| Background | This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Synonyms | AMHR; MISR2; MISRII; MRII |
| Reference Data | |
| Protein Categories | Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Single-cell transcriptome dissection of the toxic impact of Di (2-ethylhexyl) phthalate on primordial follicle assembly
Wang, Tian, Li et al
Theranostics (2021) 11 (10), 4992-5009 DOI: 10.7150/thno.55006
Wang, Tian, Li et al
Theranostics (2021) 11 (10), 4992-5009 DOI: 10.7150/thno.55006
Cited by 59
AI Summary: In this study, OriGene products including the anti-LHX8 antibody (TA322619) and anti-BMPR1A antibody (TA322357) were used for immunohistochemical staining and Western blotting to validate gene expression changes identified by single-cell RNA sequencing, thereby contributing to the elucidation of DEHP’s toxic effects on ovarian follicle assembly.
Showing 1-1 of 1 papers.
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