NADPH oxidase 4 (NOX4) Rabbit Polyclonal Antibody

SKU
TA323912
Anti-NOX4 Rabbit Polyclonal Antibody
$305.00
In Stock*
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 25-100
Positive control: Human gasrtic cancer
Predicted cell location: cytoplasm, Nucleus
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 210-424 amino acids of human NADPH oxidase 4
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name NADPH oxidase 4
Database Link
Background This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction; cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Synonyms KOX; KOX-1; RENOX
Reference Data
Protein Families Druggable Genome, Transmembrane
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