NADPH oxidase 4 (NOX4) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 25-100 Positive control: Human gasrtic cancer Predicted cell location: cytoplasm, Nucleus |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 210-424 amino acids of human NADPH oxidase 4 |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | NADPH oxidase 4 |
| Database Link | |
| Background | This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction; cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants. |
| Synonyms | KOX; KOX-1; RENOX |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Efficacy of Obcordata A from Aspidopterys obcordata on Kidney Stones by Inhibiting NOX4 Expression
Li, Ma, Lv et al
Molecules (2019) 24 (10) DOI: 10.3390/molecules24101957
Li, Ma, Lv et al
Molecules (2019) 24 (10) DOI: 10.3390/molecules24101957
AI Summary: OriGene products contributed to this study by providing antibodies against NOX4, P38, JNK, OPN, MCP-1, and GAPDH, which were used for immunoblotting and protein expression analysis.
Snippet: 4. Materials and Methods. 4.1. Antibodies and Reagents. The antibodies against NOX4, P38, JNK, OPN, MCP-1, and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) were obtained from OriGene Technologies (Rockville, MD, USA) Cached;
Antihypertensive effect of etamicastat in dopamine D2 receptor-deficient mice
Armando, Asico, Wang et al
Hypertens. Res. (2018)
Armando, Asico, Wang et al
Hypertens. Res. (2018)
AI Summary: OriGene's D1R antibody (Rockville, MD) was used in this study to assess renal D1 receptor protein expression, contributing to the evaluation of etamicastat's effects on dopamine receptor regulation in D2 receptor-deficient mice.
Snippet: Louis, MO) were purchased. We have reported the specificity of our D 1 R antibody [18, 20], D 3 R antibody [19], D 4 R antibody [17], D 5 R antibody [21, 22], D 1 R antibody from Origene (Rockville, MD) [22], and D 2 R from EMD Millipore [13]
Showing 1-2 of 2 papers.
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