IL11RA Rabbit Polyclonal Antibody

CAT#: TA323905

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Anti-IL11RA Rabbit Polyclonal Antibody



USD 380.00


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Size
    • 100 ul


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Specifications

Product Data
Applications WB
Recommended Dilution WB: 500-2000
WB positive control: 293T cells
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 185-371 amino acids of Human Interleukin-11 receptor subunit alpha
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 45 kDa
Gene Name interleukin 11 receptor subunit alpha
Background Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor; which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor; since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.
Synonyms CRSDA
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway
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