TRAF3IP1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 200-1000 WB positive control: Mouse thymus tissue IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from C terminal 250 amino acids of human TNF receptor-associated factor 3 interacting protein 1 |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 79 kDa |
| Gene Name | TRAF3 interacting protein 1 |
| Database Link | |
| Background | This protein plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. It can interacts with IL13RA1 and binds to microtubules, TRAF3 and DISC1. |
| Synonyms | IFT54; MIP-T3; MIPT3; SLSN9 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
MIP-T3 Expression Associated with Defects of Ciliogenesis in Airway of COPD Patients
Wang, Yang, Gao et al
Can Respir J (2020) 2020, 1350872 DOI: 10.1155/2020/1350872
Wang, Yang, Gao et al
Can Respir J (2020) 2020, 1350872 DOI: 10.1155/2020/1350872
Cited by 2
AI Summary: In this paper, OriGene products—including the human MIP-T3 cDNA clone (RC200175) and MIP-T3-specific antibodies (TA500628)—were used to measure MIP-T3 mRNA and protein expression, helping to demonstrate that reduced MIP-T3 levels are associated with abnormal cilia structure in the airways of COPD patients.
Showing 1-1 of 1 papers.
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