BTG3 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 1000-5000 WB positive control: Mouse testis tissue lysate IHC: 100-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 22-252 amino acids of human BTG family, member 3BTG family, member 3 |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 29 kDa |
| Gene Name | BTG family member 3 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase. |
| Synonyms | ANA; APRO4; TOB5; TOB55; TOFA |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
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Citations
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3
Zhang, Li, Zhu et al
Cell Death Dis (2024) 15 (5), 355 DOI: 10.1038/s41419-024-06741-3
Zhang, Li, Zhu et al
Cell Death Dis (2024) 15 (5), 355 DOI: 10.1038/s41419-024-06741-3
Cited by 23
AI Summary: In this study, the OriGene BTG3 antibody (TA323849) was used to detect BTG3 protein levels, enabling the researchers to investigate the role of TRIM65-mediated ubiquitination and degradation of BTG3 in promoting renal cell carcinoma.
Snippet: Reagents MG132, CHX, TRIM65 antibody (HPA021578) was purchased from Sigma-Aldrich (St.Louis, MO, USA). Fascaplysin was purchased from GlpBio (Montclair, CA, USA). BTG3 antibody (TA323849) was from OriGene (Rockville, MD, USA). K63-linkage specific Ub (5621 S), K48-linkage specific Ub (8081 S), and Ub (3936 S) were purchased from Cell Signaling Technology (Danvers, MA, USA). GFP (66002-1-I
Propofol alleviates hypoxia-induced nerve injury in PC-12 cells by up-regulation of microRNA-153
He, Sun, Pang et al
BMC Anesthesiol (2018) 18 (1), 197 DOI: 10.1186/s12871-018-0660-z
He, Sun, Pang et al
BMC Anesthesiol (2018) 18 (1), 197 DOI: 10.1186/s12871-018-0660-z
Showing 1-2 of 2 papers.
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