SLC8A3 Rabbit Polyclonal Antibody

CAT#: TA323836

Anti-SLC8A3 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA323836 (SLC8A3 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA323836 (SLC8A3 Antibody) at dilution 1/70, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 100-300
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm, Nucleus
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 33-47 amino acids of Human solute carrier family 8 (sodium/calcium exchanger), member 3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: solute carrier family 8 member A3
• Database Link:
  NP_891978
  Entrez Gene 6547 Human
  UniProt ID P57103
• Background: This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes; where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.
• Synonyms: Ca(2+)-exchange protein 3; Ca2+ exchanger 3; calcium exchan; calcium exchanger SLC8A3; member 3; Na(+); Na+; NCX3; OTTHUMP00000179116; sodium; sodium-calcium exchanger form 3; solute carrier family 8 (sodium; solute carrier family 8 (sodium-calcium exchanger)

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Calcium signaling pathway