SLC8A3 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 100-300 Positive control: Human lung cancer Predicted cell location: Cytoplasm, Nucleus |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 33-47 amino acids of Human solute carrier family 8 (sodium/calcium exchanger), member 3 |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | solute carrier family 8 member A3 |
| Database Link | |
| Background | This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes; where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. |
| Synonyms | Ca(2+)-exchange protein 3; Ca2+ exchanger 3; calcium exchan; calcium exchanger SLC8A3; member 3; Na(+); Na+; NCX3; OTTHUMP00000179116; sodium; sodium-calcium exchanger form 3; solute carrier family 8 (sodium; solute carrier family 8 (sodium-calcium exchanger) |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Transmembrane |
| Protein Pathways | Calcium signaling pathway |
Reviews
Documents
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Citations
Chronic pharmacological blockade of the Na(+) /Ca(2+) exchanger modulates the growth and development of the Purkinje cell dendritic arbor in mouse cerebellar slice cultures
Sherkhane, Kapfhammer
Eur. J. Neurosci. (2017)
Sherkhane, Kapfhammer
Eur. J. Neurosci. (2017)
AI Summary: In this study, the OriGene rabbit polyclonal anti-NCX3 antibody (cat #: TA323836) was used as a primary antibody to detect NCX3 expression in cerebellar slice cultures, helping to assess the role of NCX isoforms in Purkinje cell dendritic development.
Snippet: studies, rabbit polyclonal anti-NCX1 (Alomone labs, Israel, cat #: ANX-011), 1:100, and rabbit polyclonal anti-NCX3 (cat #: TA323836), 1:1000 (Origene, United States) were used as primary antibodies and goat anti-rabbit Alexa 488 (Molecular Probes, Invitrogen, 1: ... … studies, rabbit polyclonal anti-NCX1 (Alomone labs, Israel, cat #: ANX-011), 1:100, and rabbit polyclonal anti-NCX3 (cat #: TA323836), 1:1000 (Origene, United States) were used as primary antibodies and goat anti-rabbit Alexa 488 (Molecular Probes, Invitrogen, 1: ... …
Showing 1-1 of 1 papers.
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