NMDAR2C (GRIN2C) Rabbit Polyclonal Antibody

SKU
TA323552
Anti-GRIN2C Rabbit Polyclonal Antibody
  $305.00
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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 100-300
Positive control: Human lung cancer
Predicted cell location: Nucleus, Cytoplasm
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 1201-1215 amino acids of human glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name glutamate ionotropic receptor NMDA type subunit 2C
Database Link
Background N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation; an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A); NMDAR2B (GRIN2B); NMDAR2C (GRIN2C); and NMDAR2D (GRIN2D).
Synonyms GluN2C; NMDAR2C; NR2C
Reference Data
Protein Categories Membrane Proteins
Protein Families Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Long-term potentiation, Neuroactive ligand-receptor interaction
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