FAT3 Rabbit Polyclonal Antibody

SKU TA323469

Anti-FAT3 Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 25-100; Positive control: Human liver cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 3985-4000 amino acids of human FAT tumor suppressor homolog 3 (Drosophila)
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: FAT atypical cadherin 3
• Database Link:
  NP_001008781
  Q8TDW7
• Background: FAT1; FAT2; FAT3 and FAT4 are human homologs of Drosophila Fat; which is involved in tumor suppression and planar cell polarity (PCP). The atypical cadherin Fat3 ensures that retinal amacrine cells (ACs) develop this unipolar morphology. Fat3 expression was restricted to the nervous system; for example in the brain; it is expressed in a variety of regions and axon fascicles. However; its strongest expression was observed in the olfactory bulb and retina.
• Synonyms: CDHF15; CDHR10; hFat3

Reference Data