FOXB2 Rabbit Polyclonal Antibody

SKU TA323431

Anti-FOXB2 Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 10-50; Positive control: Human gasrtic cancer; Predicted cell location: Cytoplasm, Nucleus
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 411-424 amino acids of Human Forkhead box B2
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: forkhead box B2
• Database Link:
  NP_001013757
  Q5VYV0
• Background: FOX?(Forkhead box)?proteins?are a family of?transcription factors?that play important roles in regulating the expression of?genes?involved in cell growth; proliferation; differentiation; and?longevity. Many FOX proteins are important to embryonic development. The defining feature of FOX proteins is the forkhead box; a sequence of 80 to 100 amino acids forming a motif that binds to DNA. This forkhead motif is also known as the winged helix due to the butterfly-like appearance of the loops in the protein structure of the domain. Forkhead genes are a subgroup of the helix-turn-helix class of proteins. The FOXF2 gene encodes forkhead box F2; one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta.
• Synonyms: bA159H20.4

Reference Data