IL18BP Rabbit Polyclonal Antibody

CAT#: TA323375

Anti-IL18BP Rabbit Polyclonal Antibody


 Product Datasheet for 'TA323375'

USD 335.00


Availability*
In Stock

Size
    • 100 ul


Product images

Specifications

Product Data
Applications IHC
Recommend Dilution ELISA: 1:500-5000, IHC: 1:50-200
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 31-195 of Human Interleukin-18-binding protein
Isotype IgG
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 0.6mg/ml
Purification Antigen affinity purification
Gene Name interleukin 18 binding protein
Background The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine; IL18. It binds IL18; prevents the binding of IL18 to its receptor; and thus inhibits IL18-induced IFN-gamma production; resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms IL18BPa
Reference Data
Protein Families Secreted Protein, Druggable Genome
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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