CDK9 Rabbit Polyclonal Antibody

CAT#: TA323196

Anti-CDK9 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: 823 cells Hela cells Primary antibody: TA323196 (CDK9 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 40 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 823 and Hela cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 19-315 amino acids of human cyclin-dependent kinase 9
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 53 kDa
• Gene Name: cyclin-dependent kinase 9
• Database Link:
  NP_001252
  Entrez Gene 107951 MouseEntrez Gene 362110 RatEntrez Gene 1025 Human
  UniProt ID P50750
• Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28; and S. pombe cdc2; and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb; which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T; which suggested a possible involvement of this protein in AIDS.
• Synonyms: C-2k; CDC2L4; CTK1; PITALRE; TAK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transcription Factors