CDK9 Rabbit Polyclonal Antibody

SKU
TA323196
Anti-CDK9 Rabbit Polyclonal Antibody
  $305.00
In Stock*
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Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 500-2000
WB positive control: 823 and Hela cells
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 19-315 amino acids of human cyclin-dependent kinase 9
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 53 kDa
Gene Name cyclin-dependent kinase 9
Database Link
Background The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28; and S. pombe cdc2; and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb; which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T; which suggested a possible involvement of this protein in AIDS.
Synonyms C-2k; CDC2L4; CTK1; PITALRE; TAK
Reference Data
Protein Categories Cytokines, Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase, Transcription Factors
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