FGF4 Rabbit Polyclonal Antibody

CAT#: TA323076

Anti-FGF4 Rabbit Polyclonal Antibody

Antibody Service

 Product Datasheet for 'TA323076'

USD 335

In Stock

    • 100 ul

Product images


Product Data
Applications IHC
Recommend Dilution ELISA: 1:1000-10000, IHC: 1:50-150
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 192-206 amino acids of Human fibroblast growth factor 4
Isotype IgG
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 1.9mg/ml
Purification Antigen affinity purification
Gene Name fibroblast growth factor 4
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development; cell growth; morphogenesis; tissue repair; tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3; another oncogenic growth factor; are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
Reference Data
Protein Families Stem cell relevant signaling - Wnt Signaling pathway, Secreted Protein, ES Cell Differentiation/IPS, Transmembrane, Adult stem cells, Embryonic stem cells, Induced pluripotent stem cells, Druggable Genome
Protein Pathways MAPK signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Melanoma
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.