LRPAP1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 500-2000 WB positive control: 293T cells and fetal kidney tissue IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 344-357 amino acids of Human low density lipoprotein receptor-related protein associated protein 1 |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 41 kDa |
| Gene Name | LDL receptor related protein associated protein 1 |
| Database Link | |
| Background | Low density lipoprotein receptor-related protein associated protein 1?also known as?LRPAP1?or?RAP?is a chaperone?protein?which in humans is encoded by the LRPAP1?gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor; as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors; and may prevent receptor aggregation and degradation in the endoplasmic reticulum; thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin; since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II. |
| Synonyms | A2MRAP; A2RAP; alpha-2-MRAP; HBP44; MRAP; MYP23; RAP |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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