SLC10A1 Rabbit Polyclonal Antibody

CAT#: TA322912

Anti-SLC10A1 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA322912 (SLC10A1 Antibody) at dilution 1/31 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA322912 (SLC10A1 Antibody) at dilution 1/31, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 15-50
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 2-15 amino acids of Human solute carrier family 10 (sodium/bile acid cotransporter family), member 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: solute carrier family 10 member 1
• Database Link:
  NP_003040
  Entrez Gene 20493 MouseEntrez Gene 6554 Human
  UniProt ID Q14973
• Background: The protein encoded by this gene belongs to the sodium/bile acid cotransporter family; which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen; bile duct and kidney; and the liver-specific sodium/bile acid cotransporter; represented by this protein; that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism; hence this protein is important for cholesterol homeostasis.
• Synonyms: NTCP

Reference Data

• Protein Families: Druggable Genome, Transmembrane