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SLC4A7 Rabbit Polyclonal Antibody

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SKU
TA322834
Anti-SLC4A7 Rabbit Polyclonal Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $305.00
4 Weeks*
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View other "SLC4A7 or NM_003615" antibodies

Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 50-200
Positive control: Human brain
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 1201-1214 amino acids of Human solute carrier family 4, sodium bicarbonate cotransporter, member 7
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name solute carrier family 4 member 7
Database Link
Background This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio; and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Synonyms NBC2; NBC3; NBCN1; SBC2; SLC4A6
Reference Data
Protein Categories Growth Factors, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
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Documents
Resources

file-alt Citations

Microenvironmental acidosis drives PARP- and ATM inhibitor resistance in p53 deficient pancreatic cancer
Ialchina, Simonsen, Andersen et al
iScience (2026)
Cited by 1
AI Summary: In the paper "Microenvironmental acidosis drives PARP- and ATM inhibitor resistance in p53 deficient pancreatic cancer," OriGene's NBCn1 antibody (Cat#TA322834) was used for immunofluorescence experiments to study protein expression related to drug resistance mechanisms.
Snippet: NHE1 (IF) Santa Cruz Biotechnology Cat#sc-136239, RRID:AB_2191254 NBCn1 (IF) Origene Cat#TA322834, RRID:AB_2749851 CFTR (IF) Thermo Fisher Scientific. Cat#MA1-935, RRID:AB_2081230 RasG12D Cell Signaling Technology Cat#sc-14429, RRID:AB_2728748
The apical Na+ -HCO3- cotransporter Slc4a7 (NBCn1) does not contribute to bicarbonate transport by mouse salivary gland ducts
Yang, Mukaibo, Kurtz et al
J. Cell. Physiol. (2019)
AI Summary: OriGene's rabbit anti-Slc4a7 antibody (Cat# TA322834) was used to immunolocalize Slc4a7 in mouse salivary gland tissues, helping determine its cellular distribution and role in bicarbonate transport.
Snippet: Skip to Main Content;Sections were blocked in 1% bovine serum albumin (BSA) in phosphate‐buffered saline (PBS) for 30 min at room temperature (RT), and then incubated at 4°C with rabbit anti‐Slc4a7 (1:100 dilution, Cat# TA322834, RRID: AB_2749851;OriGene, Rockville, MD) and goat anti‐Slc12a2 (Nkcc1, 1:100 dilution, Cat# sc‐21545, RRID: AB_2188633;Santa Cruz Biotechnology, Dallas, TX) antibodies overnight
IHC
Showing 1-2 of 2 papers.
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