VNN2 Rabbit Polyclonal Antibody
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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
USD 200.00
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 200-1000 WB positive control: K562 and hela cells |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 389-401 amino acids of human vanin 2 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 59 kDa |
Gene Name | vanin 2 |
Database Link | |
Background | This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other; and also with biotinidase. The family includes secreted and membrane-associated proteins; a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins; however; they possess pantetheinase activity; which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to; and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Synonyms | FOAP-4; GPI-80 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Documents
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.