SIPA1 Rabbit Polyclonal Antibody

SKU TA322474

Anti-SIPA1 Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human colon cancer; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1030-1042 amino acids of human signal-induced proliferation-associated 1
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: signal-induced proliferation-associated 1
• Database Link:
  NP_006738
  Q96FS4
• Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2; but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
• Synonyms: SPA1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: Leukocyte transendothelial migration